Wuhan Biocar Bio-Pharm Co., Ltd.  

Product Name: Factory Direct Semi-Synthetic Glycopeptide Antibiotic Pharmaceutical Raw Material Dalbavancin (CAS: 171500-79-1) Model NO.: PHARMACEUTICAL GRADE Purity: >99% State: Solid Suitable for: Feed Certification: GMP, ISO 9001 Customized: Non-Customized Powder: Yes Product Name: Dalbavancin Model No.: Cyn-271 Molecular Formula: C88h100cl2n10o28 Molecular Weight: 1816.69 Product Specifications: Pharmaceutical Grade MOQ: 100g Origion: Hubei, China Market: Global Trademark: Biocar Transport Package: Aluminum Foil Bags or Fiber Drum Specification: SGS Origin: Wuhan, Hubei, China HS Code: 0000000000 Product Description Factory Direct Antibotic Dalbavancin with High Purity(CAS: 171500-79-1)=====================================Chemical Information:Quick Details:Product nameDalbavancinCAS NO.171500-79-1CategoryPharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.Standardpurity:>99%AppearanceDalbavancin powderShelf life2 yearsUsageDalbavancin is anovel second-generation lipoglycopeptide antibiotic.StorageDalbavancin should be stored in awell-closed container at low temperature, keep away from moisture, heat and light.Product Name: DalbavancinModel No.: CYN-271CAS No.: 171500-79-1Molecular Formula: C88h100cl2n10o28Molecular Weight: 1816.69Appearance: White Crystalline powderMelting Point: N/ACOA: AvailableMSDS: AvailableSpectrum: AvailablePurity: 99%+Suitable People: ALL PeopleProduct Specifications: Pharmaceutical GradeStandard: QualifiedMOQ(Minimum Order Quantity): 10gPayment: L/C, T/T, Western UnionShipment: EMS, DHL, FedExPacking: Aluminium Foil Bag or as Required =====================================Product Description:Dalbavancin is anovel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).Dalbavancin is asemisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.Puhopharma specializes in controling the quality and reducing the impurities of Dalbavancin.Our Dalbavancin is with the best quality and the most competitive price in China.Dalbavancin (INN, trade names Dalvance in the US and Xydalba in Europe) is anovel second-generation lipoglycopeptide antibiotic. It belongs to the same class, the most widely used and one of the few treatments available to patients infected with methicillin-resistant Staphylococcus aureus (MRSA).Dalbavancin is asemisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available.It possesses in vitro activity against avariety of Gram-positive pathogens including MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE).It is aonce-weekly, two-dose antibiotic, the rights to which Actavis acquired when it bought Durata Therapeutics in 2014.The Food and Drug Administration approved dalbavancin in May 2014 for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by certain susceptible bacteria such as Staphylococcus aureus including methicillin-susceptible and methicillin-resistant strains of Streptococcus pyogenes, in intravenous dosage form.=====================================Applications/Usage:Dalbavancin is an antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) in adults caused by susceptible Gram-positive organisms, including methicillin-resistant Staphylococcus aureus(MRSA).It has strong activity against many Gram-positive bacteria, including methicillin-sensitive and methicillin-resistant Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus anginosus,Streptococcus intermedius, and Streptococcus constellatus.Dalbavancin is asemi-synthetic glycopeptide prepared from A40926 by introducing apositively charged lipophilic moiety in apreviously unexplored region of the natural glycopeptide. This modification provides alonger in vivo half life, and improved in vitro activity against avariety of Gram positive and multi-drug resistant isolates such as MRSA and MRSE.=====================================Drug Interaction:Clinical drug-drug interactions with dalbavancin have not been studied, and dalbavancin does not appear to interact with cytochrome P450 substrates, inhibitors, or inducers. It was found to have an in vitro synergistic interaction with the antimicrobial oxacillin, but the clinical significance of this interaction has yet to be established.=====================================Mechanism of Action:Dalbavancin is alipoglycopeptide belonging in the same glycopeptide class. Similar to other glycopeptides, dalbavancin exerts its bactericidal effect by disrupting cell wall biosynthesis. It binds to the D-alanyl-D-alanyl residue on growing peptidoglycan chains and prevents transpeptidation from occurring, preventing peptidoglycan elongation and cell wall formation. Dalbavancin also dimerizes and anchors itself in the lipophilic bacterial membrane, thereby increasing its stability in the target environment and its affinity for peptidoglycan.Antimicrobial activity correlates with the ratio of area under the concentration-time curve to minimum inhibitory concentration for Staphylococcus aureus.=====================================Side Effects:The most common adverse reactions encountered in Phase II and Phase III trials were nausea (5.5%), headache (4.7%), and diarrhea (4.4%), as well as rash (2.7%) and itchiness (2.1%).=====================================COA:ItemsStandardDescriptionWhite or almost white, crystalline powderWater≤0.5%Residue on ignition≤0.1Limit of chlorideNMT0.03%Heavy metalsNMT0.001%MethanolNMT0.1%AlcoholNMT0.1%Related components ANMT0.5%Any unknown impurityNMT0.10%Total impuritiesNMT2.0%Assay98.0%~102.0%FEATURED PRODUCT:Wuhan Newbio Pharm-tech Co., Ltd.S#CAS No.Product NameS#CAS No.Product Name186639-52-37-Ethyl-10-Hydroxycamptothecin25183321-74-6Erlotinib2154229-18-2Abiraterone Acetate26183319-69-9Erlotinib Hydrochloride350-76-0Actinomycin D27159351-69-6Everolimus4106941-25-7Adefovir2856296-78-7Fluoxetine Hydrochloride5850140-72-6Afatinib29184475-55-6Gefitinib Hydrochloride6330784-47-9Avanafil30136572-09-3Irinotecan HydrochlorideTriHydrate7319460-85-0Axitinib311441674-54-9Ledipasvir(Acetone)81421373-66-1AZD-9291 (Mesylate)32191732-72-6Lenalidomide9123524-52-7Azelnidipine3321672Methotrexate10863031-21-4Azilsartan Medoxomil3476144-81-5Mildronate11179324-69-7Bortezomib35474645-27-7Monomethyl Auristatin E12357336-20-0Brivaracetam3663121-00-6Oxaliplatin13842133-18-0Canagliflozin4933069-62-4Paclitaxel14928672-86-0Canagliflozin HemiHydrate37137281-23-3Pemetrexed Disodium1541575-94-4Carboplatin3853123-88-9Rapamycin1650935-04-1Carubicin50135062-02-1Repaglinide17288383-20-0Cediranib39945667-22-1Saxagliptin Hydrate1815663-27-1Cisplatin40709031-78-7Saxagliptin Hydrochloride19877399-52-5Crizotinib41486460-32-6Sitagliptin20171500-79-1Dalbavancin42654671-77-9Sitagliptin Phosphate Hydrate21114977-28-5Docetaxel4485622-93-1Temozolomide22148408-66-6Docetaxel TriHydrate45477600-75-2Tofacitinib2325316-40-9Doxorubicin hydrochloride46540737-29-9Tofacitinib Citrate24133040-01-4Eprosartan47170791-09-0Trityl Candesartan Cilexetilabout DELIVERY:#1 Products can be sent out within 24 hours after payment.#2 Secure and discreet shipment.#3 Various methods for your choice, like DHL/FedEx/SF-express.OUR COMMITMENT:#1 We are manufacturer with own factory and we sale this product at abest quality and low price.#2 All product listed is available in stock, please contact the sale for more details.#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.If you want to source ... #1 Pharmaceutical raw material, #2 oncology drug APIs, #3 Antibiotics or fine chemicals,We are areliable manufacturer and supplier in China.NEWBIO would like to ... #1 We foucus on the high purity and high quality; #2 We provide the raw materials at agood price; #3 We have the best service and we are always there for you.Please contact us for more infomation!!!