Wuhan Biocar Bio-Pharm Co., Ltd.  

Product Name: Effective Small-Molecule Inhibitor Afatinib (CAS: 439081-18-2) Model NO.: Pharmaceutical Grade Product Name: Afatinib Model No.: Atb-136 Molecular Formula: C24h25clfn5o3 Molecular Weight: 485.94 Product Specifications: Pharmaceutical Grade MOQ(Minimum Order Quantity): 10g Origion: Hubei, China Brand: Newbio Pharmtech Market: Global Trademark: NEWBIO PHARMTECH Transport Package: Aluminum Foil Bags or Fiber Drum Specification: SGS/ CTI/ ITS Origin: Wuhan, Hubei, China HS Code: 8676530000 Product Description Small-Molecule Targeted Anti Tumor Inhibitor API Afatinib(CAS: 439081-18-2)Chemical InformationQuick Details:Product NameAfatinibMolecular FormulaC24H25ClFN5O3Molecular Weight485.94Storage3years in -20ºCTargetsAbl c-SrcDosage30 nM; intraperitoneal injectionTargetEGFR (L858R)EGFR (wt)EGFR (L858R/T790M)HER2IC500.4 nM0.5 nM10 nM14 nMProduct Name: AfatinibOther Names:Afatinib;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dime;Afatinib API;Afatinib(BIBW2992MA2);Afatinib (with 1int.)Model No.: ATC-136CAS No.: 439081-18-2Molecular Formula: C24H25ClFN5O3Molecular Weight: 485.94Appearance: White or Nearly White Crystalline PowderPurity: 99%+Product Specifications: Pharmaceutical Grade Product DescriptionAfatinib (INN; trade name Gilotrif in the US and Giotrif in Europe, previously Tomtovok and Tovok) is adrug approved in United States, Europe, Taiwan, Mexico, Chile and Japan as well as other countries for the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It acts as an irreversible covalent inhibitor of the receptor tyrosine kinases epidermal growth factor receptor (EGFR) and erbB-2 (HER2).Applications/UsageIt has received regulatory approval for use as atreatment for non-small cell lung cancer, although there is emerging evidence to support its use in other cancers such as breast cancer.COA Report:ItemRequirementsTest ResultsDescriptionOff-whitepowderOff-whitepowderIdentificationHPLC ,NMRCompliesResidue on Ignition≤0.10%0.05%Loss on Drying≤0.50%0.15%Heavy metal≤20ppm<20ppmPurity(HPLC)≥99.0%99.99%ConclusionIt complies with EnterpriseStandardFEATURED PRODUCT:No.CAS No.Product Name1114977-28-52148408-66-6325316-40-94133040-01-4Eprosartan5183321-74-6Erlotinib6183319-69-9Erlotinib Hydrochloride7159351-69-6Everolimus856296-78-7Fluoxetine Hydrochloride9184475-55-610136572-09-3111441674-54-9Ledipasvir(Acetone)12191732-72-6Lenalidomide13216721476144-81-5Mildronate15474645-27-7Monomethyl Auristatin E1663121-00-617137281-23-3Pemetrexed Disodium1853123-88-9Rapamycin19945667-22-1Saxagliptin Hydrate20709031-78-7Saxagliptin Hydrochlorideabout DELIVERY:#1 Products can be sent outwithin 24 hoursafter payment.#2Secure and discreetshipment.#3Various methodsfor your choice, like DHL/FedExs.OUR COMMITMENT:#1 We aremanufacturerwith own factory and we sale this product at abest quality and low price.#2 All product listed isavailable in stock, please contact the sale for more details.#3 We haveQA&QC departmenttoguarantees the quality,productpass ratecan reach100%.ConTACT US:Telephone+86-027-87002705Mobile+86-13277093700+86-13638641831FaceBook Pagehttps://www.facebook.com/newbiopharma/Facebook Grouphttps://www.facebook.com/groups/1739616069613416/Websitehttp://www.newbiopharm.com/online Storehttp://biocar.en.made-in-china.com/If you want to source ... #1 Pharmaceutical raw material, #2 oncology drug APIs, #3 Antibiotics or fine chemicals,We are areliable manufacturer and supplier in China.NEWBIO would like to ... #1 We foucus on the high purity and high quality; #2 We provide the raw materials at agood price; #3 We have the best service and we are always there for you.Please contact us for more infomation!!!